TCRm Therapeutic Antibodies
Targeting a new class of disease specific biomarkers, our products provide next generation treatments for cancer, infectious disease, and chronic disease.
Receptor Logic's T-Cell Receptor mimic monoclonal antibodies (TCRm) recognize specific and individual Major Histocompatibility Complex (MHC-complexes) peptide complexes, thereby allowing soluble reagents to identify diseased cells with great specificity. The binding of the TCRms to MHC-peptide complexes allows researchers to measure peptide antigen expression on diseased cells, monitor the immune response of individuals, and in concert with the body's immune system, directly control and eliminate the diseased cells. These capabilities offer a modality that can simultaneously assist in disease diagnosis and patient qualification, while also acting as a therapeutic agent.
TCRms provide hope to patients by offering next generation therapeutic options to cancer and other diseases that, until today, were inaccessible. Please contact us for a full data package.
For product overview: Therapeutic Antibodies (pdf)
TCRm Potency Assay Services
Targeting the critical need for potency measurements, our services provide biopharma partners quantitative solutions for their immunotherapeutic products.
Unlike traditional chemically compounded drugs, vaccines are produced from organisms and suitable methods of verifying lot to lot potency (the specific activity of therapy needed to produce a measured, quantitative and clinically relevant effect) continues to be a significant challenge for the FDA and vaccine manufacturers, especially those creating next generation therapeutic vaccines.
Receptor Logic's TCRm products address this critical question of vaccine and active immunotherapy potency. TCRm technology facilitates immunotherapy product potency measurement at four distinct points:
- Assisting in lead antigen validation
- Demonstrating lot to lot consistency of released drug substance
- Providing stability indicating measurements supporting product shelf life
- Measurement of specific immune responses in clinical trials.
Please contact us and we will provide a complete description of services offered and explore how Receptor Logic's TCRm technology may assist your product development efforts.
For product overview: Assay Services (pdf)
TCRm Immunology Reagent Products
Targeting scientific understanding, our reagents illuminate, quantify, and characterize the immune response expanding research capabilities.
Receptor Logic's TCRms recognize many peptide antigens used in discovery and product development research. The TCRms can immediately integrate into and provide a quantitative baseline for a number of established assays, including:
- Immunocytochemical staining
- Flow cytometry
- Antigen priming
- Cytotoxic T lymphocyte
If you wish to test our antibodies in your research, please view our catalog below or contact us.
For product overview: Immunology Reagent Products (pdf)